Vincent Wang, Ph.D.

Kevin P. Granata Faculty Fellow and Associate Professor
Wang Vincent 1
339 Kelly Hall
325 Stanger St.
Blacksburg, VA 24061

Lab

Orthopedic Mechanobiology Lab

Watch this short video about the lab. All BEAM videos available here.

Research Areas

  • Biomaterials
  • Biomechanics
  • Biomedical Imaging
  • Solid mechanics

Research Interests

  • Tendon healing and repair
  • Skeletal tissue mechanobiology
  • Orthopedic biomechanics
  • Machine learning
  • Reproductive biomechanics

Education

  • Mount Sinai School of Medicine: Postdoctoral Fellowship, 2001-2005 
  • Columbia University: Ph.D., Mechanical Engineering, 2001 
  • Columbia University: M.S., Mechanical Engineering, 1996 
  • Columbia University: B.S., Mechanical Engineering, 1994

Awards, Honors, and Service

Selected Awards and Honors

  • Kevin P. Granata Faculty Fellow (Virginia Tech), August 2016 - present 
  • Musculoskeletal Transplant Foundation (MTF) Junior Investigator Grant, 2011 
  • Individual National Research Service Award (NRSA), National Institutes of Health, 2003-2005 
  • Sheng Fellowship, Fu Foundation School of Engineering & Applied Science, Columbia University, 1999-00 
  • Charles S. Neer Award for basic science research, American Shoulder and Elbow Surgeons Society, 1996 

Service

  • Chair, Orthopaedic Research Society (ORS) Scientific Communications Committee, 2018-2020 
  • BMES 2018 Annual Meeting Track Chair, Orthopedics and Rehabilitation 
  • Associate Editor, Connective Tissue Research, 2015-present 
  • NIH SBSR/SBIR/STTR ad hoc reviewer, 2013-present

Recent Publications

Rezvani SN, Chen J, Li J, Midura R, Cali V, Sandy JD, Plaas A, Wang VM. In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy. J Orthop Res. 2019 Sep 3. doi: 10.1002/jor.24459. [Epub ahead of print]

Guidetti M, Zampini MA, Gandini G, Gupta A, Li W, Magin RL, Wang VM. Diffusion Tensor Imaging of Tendons and Ligaments at Ultra-High Magnetic Fields. Crit Rev Biomed Eng. 2018;46(4):311-339.

Sikes KJ, Renner K, Li J, Grande-Allen KJ, Connell JP, Cali V, Midura RJ, Sandy JD, Plaas A, Wang VM. Knockout of hyaluronan synthase 1, but not 3, impairs formation of the retrocalcaneal bursa. J Orthop Res. 2018 Oct;36(10):2622-2632.

Sikes KJ, Li J, Gao SG, Shen Q, Sandy JD, Plaas A, Wang VM. TGF-b1 or hypoxia enhance glucose metabolism and lactate production via HIF1A signaling in tendon cells. Connect Tissue Res. 2018 Sep;59(5):458-471.

Trella KJ, Li J, Stylianou E, Wang VM, Frank JM, Galante J, Sandy JD, Plaas A, Wysocki R. Genome-wide analysis identifies differential promoter methylation of Leprel2, Foxf1, Mmp25, Igfbp6, and Peg12 in murine tendinopathy. J Orthop Res. 2017 May;35(5):947-955.

Wang VM, Karas V, Lee AS, Yin Z, Van Thiel GS, Hussey K, Sumner DR, Chubinskaya S, Magin RL, Verma NN, Romeo AA, Cole BJ. Assessment of glenoid chondral healing: comparison of microfracture to autologous matrix-induced chondrogenesis in a novel rabbit shoulder model. J Shoulder Elbow Surg. 2015 Nov;24(11):1789-1800.

Friel NA, McNickle AG, DeFranco MJ, Wang F, Shewman EF, Verma NN, Cole BJ, Bach BR Jr, Chubinskaya S, Kramer SM, Wang VM. Effect of highly purified capsaicin on articular cartilage and rotator cuff tendon healing: An in vivo rabbit study. J Orthop Res. 2015 Dec;33(12):1854-60.

Bell R, Li J, Shewman EF, Galante JO, Cole BJ, Bach BR Jr, Troy KL, Mikecz K, Sandy JD, Plaas AH, Wang VM. ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy. J Orthop Res. 2013 Oct;31(10):1540-8.

Bell R, Li J, Gorski DJ, Bartels AK, Shewman EF, Wysocki RW, Cole BJ, Bach BR Jr, Mikecz K, Sandy JD, Plaas AH, Wang VM. Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model. J Biomech. 2013 Feb 1;46(3):498-505.

Brem H, Kodra A, Golinko MS, Entero H, Stojadinovic O, Wang VM, Sheahan CM, Weinberg AD, Woo SL, Ehrlich HP, Tomic-Canic M. Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing. J Invest Dermatol. 2009 Sep;129(9):2275-8.