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Alex Hyler

Adjunct Faculty
portrait of Alex Hyler in a blue blazer
CytoRecovery, Inc.
ahyler@vt.edu

Vice President and CSO of CytoRecovery, Inc. in Blacksburg, VA

Working at CytoRecovery, Dr. Hyler leads a team that is working to commercialize a novel cell sorting platform with improved cell viability, recovery, and behavior. Using label-free, microfluidics technology invented in the Davalos Laboratory (BEMS Lab) at Virginia Tech, we are developing a novel tool for cell enrichment, sorting, and recovery for applications spanning oncology, neurology, regenerative medicine, and more. Her research interests include biotechnology, commercialization, translational cancer research, nanobioengineering, and microfluidics.

Education

  • Virginia Tech: Ph.D., Biomedical Engineering, 2018
  • University of Kansas: B.S., Chemical Engineering, German minor, 2013  

Department Involvement

  • BMES 4154/5154: Commercialization of Biomedical Engineering (BME) Research

Awards, Honors, and Service

  • 2018: Virginia Tech Graduate Student of the Year
  • 2015-2016: J. William Fulbright Fellow to Copenhagen, Denmark
  • 2013-2018: NSF Interdisciplinary Graduate Education Program Fellowship

Publications

AR Hyler, D Hong, RV Davalos, NS Swami, EM Schmelz. “A Novel Ultra-Low Conductivity Electromanipulation Buffer Improves Cell Viability and Enhances Dielectrophoreitc Consistency.” Electrophoresis, 2021 (https://doi.org/10.1002/elps.202000324).

A Salahi, WB Varhue, V Farmehini, AR Hyler, EM Schmelz, RV Davalos, NS Swami. “Self-aligned microfluidic contactless dielectrophoresis device fabricated by single-layer imprinting on cyclic olefin copolymer.” Analytical and Bioanalytical Chemistry. 412:3881-3889, 2020 (https://doi.org/10.1007/s00216-020-02667-9).

V Farmehini, W Varhue, A Salahi, AR Hyler, J Cemezar, RV Davalos, NS Swami. “On-Chip Impedance for Quantifying Parasitic Voltages During AC Electrokinetic Trapping.” IEEE Trans on Biomedical Eng. 67(6):1664-1671), 2020 (10.1109/TBME.2019.2942572).

AR Hyler, NC Baudoin, MS Brown, MA Stremler, D Cimini, RV Davalos, EM Schmelz. “Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability.” PLOS ONE, 2018 (http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194170).