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Christopher Arena, Ph.D.

Collegiate Associate Professor
  • Director of Experiential Learning
Genderless Silhouette
460 Turner Street, Suite 304
Blacksburg, VA 24061

Research Areas

  • Biomedical imaging
  • Nanobioengineering
  • Translational cancer research

Research Interests

  • Medical devices
  • Pulsed electric fields for drug delivery and tumor ablation
  • Therapeutic and diagnostic ultrasound


  • Virginia Tech: Ph.D., Biomedical Engineering, 2013
  • University of Virginia: B.S., Biomedical Engineering, 2008

Awards, Honors, and Service

  • Hultquist Award, Elon University, 2016
  • College of Engineering Graduate Student of the Year, Virginia Tech, 2013
  • 1st Place Student Paper Competition, ASME Summer Bioengineering Conference, 2012
  • 1st Place Virginia Tech KnowledgeWorks Tech Transfer Challenge, 2012

Recent Publications

S Campelo, M Valerio, HU Ahmed, SL Arena, RE Neal II, Y Hu, M Emberton, and CB Arena (2017). "An Evaluation of Irreversible Electroporation Thresholds in Human Prostate Cancer and Potential Correlations to Physiological Measurements".—Applied Physics Letters: Bioengineering. 1(1): 016101.

SM Fix, A Novell, Y Yun, PA Dayton, and CB Arena (2017). "An evaluation of the sonoporation potential of low boiling point phase-change ultrasound contrast agents in vitro".—Journal of Therapeutic Ultrasound. 5(1): 7.

B Mercadal, CB Arena, RV Davalos, and A Ivorra (2017). "Avoiding Nerve Stimulation in Irreversible Electroporation: A Numerical Modeling Study".—Physics in Medicine and Biology. 62(20): 8060.

A Novell, CB Arena, O Oralkan, and PA Dayton (2016). "Wideband acoustic activation and detection of droplet vaporization events using a capacitive micromachined ultrasonic transducer".—JASA Express Letters. 139(6): 3193-3198.

TR Porter, CB Arena, S Sayyed, J Lof, RR High, F Xie, and PA Dayton (2016). "Targeted Transthoracic Acoustic Activation of Systemically Administered Nanodroplets to Detect Myocardial Perfusion Abnormalities".—9: e003770.

CB Arena*, A Novell*, PS Sheeran, C Puett LC Moyer, and PA Dayton (2015). "Dual Frequency Acoustic Droplet Vaporization Detection for Medical Imaging".—IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 62(9): 1623-33.

CB Arena*, PA Garcia*, MB Sano*, JD Olson, T Rogers-Cotrone, JH Rossmeisl Jr., RV Davalos (2014). "Focal Blood-Brain-Barrier Disruption With High-Frequency Pulsed Electric Fields".—Technology. 2(03): 206-213.

CB Arena*, CS Szot*, PA Garcia, MN Rylander, RV Davalos (2012). "A Three-Dimensional in vitro Tumor Platform for Modeling Therapeutic Irreversible Electroporation".—Biophysical Journal. 103(9).

CB Arena, RL Mahajan, MN Rylander, RV Davalos (2012). "Towards the Development of Latent Heat Storage Electrodes for Electroporation-based Therapies".—Applied Physics Letters. 101(9).

CB Arena, MB Sano, JH Rossmeisl Jr., JL Caldwell, PA Garcia, MN Rylander, RV Davalos (2011). "High-Frequency Irreversible Electroporation for Non-Thermal Ablation without Muscle Contraction".—BioMedical Engineering OnLine. 10:102 (Highly-Accessed).