Scott Verbridge, Ph.D.

Associate Professor

Research Areas

  • Biomaterials
  • Biomedical imaging
  • Neuroengineering
  • Tissue Engineering
  • Translational Cancer Research

Research Interests

The Verbridge Laboratory of Integrative Tumor Ecology (LITE) is an NSF- and NIH-supported lab in the emerging field of tumor engineering. We place a particular emphasis on the development of simple engineered platforms that can provide deep insights into complex biological processes in the context of the tumor microenvironment.

We currently have major efforts in two primary areas: 1) the development of new tumor-targeted ablation modalities that target the altered physics of tumors, and 2) the development of innovative tissue-engineered models to analyze dynamic host-pathogen interactions within the context of cancer.

Education

  • Cornell University: Postdoctoral Researcher, Biomedical Engineering / Chemical and Biomolecular Engineering, 2008-2011
  • Cornell University: Ph.D., Physics, 2008 
  • Cornell University: M.S., Physics, 2007 
  • University of Rochester: B.S., Physics, 2002
  • University of Rochester: B.S., Applied Mathematics, 2002 

Awards, Honors, and Service

  • 2017: NSF CAREER Award 
  • 2017: Joined the Scientific Reports Editorial Board 
  • 2017: Department of Biomedical Engineering and Mechanics Distinguished Leader in Research 
  • 2016: Department of Biomedical Engineering and Mechanics Leader in Research 
  • 2015: Virginia Tech Engineering Dean's Award for Outstanding New Assistant Professor 
  • 2015: Department of Biomedical Engineering and Mechanics Leader in Scholarship Award 
  • 2015: Virginia Tech Research Scholar of the Week

Recent Publications

Balhouse, B.N.*; Patterson, L.*; Schmelz, E.M.; Slade, D.J.; Verbridge, S.S., N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: implications for breast cancer viability and proliferation in vitro, PLoS One 2017, (12), 7, e0180372.

Cox, M.C.*; Kuliasha, A.S.*; Li, L.; Verbridge, S.S., 3D Microtissue Models to Analyze the Effects of Ultralow Dose LPS on Vascular Sprouting Dynamics in the Tumor Microenvironment, ACS Biomaterials Science and Engineering 2017, Article ASAP.

Ivey, J.W.*; Latouche, E.L.; Richards, M.L.*; Lesser, G.J.; Debinski, W.; Davalos, R.V., Verbridge, S.S., Enhancing Irreversible Electroporation by Manipulating Cellular Biophysics with a Molecular Adjuvant, Biophysical Journal 2017, 113, (2), 472-480.

Wasson, E.M.; Ivey, J.W.*; Verbridge, S.S.; Davalos, R.V., The Feasibility of Enhancing Susceptibility of Glioblastoma Cells to IRE Using a Calcium Adjuvant, Annals of Biomedical Engineering 2017, 45, (11), 2535-2547.

Goswami, I.*; Coutermarsh-Ott, S.; Morrison, R.G.*; Allen, I.C.; Davalos, R.V.; Verbridge, S.S.; Bickford, L.R., Irreversible electroporation inhibits pro-cancer inflammatory signaling in triple negative breast cancer cells, Bioelectrochemistry 2017, 113, 42-50.

Ivey, J.W.*; Bonakdar, M.; Kanitkar, A.*; Davalos, R.V.; Verbridge, S.S., Improving cancer therapies by targeting the physical and chemical hallmarks of the tumor microenvironment, Cancer Letters 2016, 380, (1), 330-339.

Ivey, J.W.*; Latouche, E.L.; Sano, M.B.; Rossmeisl, J.H.; Davalos, R.V.; Verbridge, S.S., Targeted cellular ablation based on the morphology of malignant cells, Scientific Reports 2015, 5, 17157.

Hosseini, Y.*; Agah, M.; Verbridge, S.S., Endothelial cell sensing, restructuring, and invasion in collagen hydrogel structures, Integrative Biology 2015, 7, (11), 1432-1441.

Verbridge, S.S.; Chakrabarti, A.; Del Nero, P.; Kwee, B.; Varner, J.D.; Stroock, A.D.; Fischbach, C., Physicochemical regulation of endothelial sprouting in a 3-D microfluidic angiogenesis model, Journal of Biomedical Materials Research: Part A 2013, 101, (10), 2948-2956.

Choi, N.W.#; Verbridge, S.S.#; Williams, R.M.; Chen, J.; Kim, J.Y.; Schmehl, R.; Farnum, C.E.; Zipfel, W.R.; Fischbach, C.; Stroock, A.D., Phosphorescent nanoparticles for quantitative measurements of oxygen profiles in vitro and in vivo, Biomaterials 2012, 33, (9), 2710-2722 (#co-first authors).


Genderless Silhouette
  • (540) 231-6908
  • sverb@vt.edu
  • 345 Kelly Hall
    325 Stanger St.
    Blacksburg, VA 24061