Scott Verbridge, Ph.D.

Associate Professor
Genderless Silhouette
345 Kelly Hall
325 Stanger St.
Blacksburg, VA 24061

Research Areas

  • Biomaterials
  • Biomedical imaging
  • Neuroengineering
  • Tissue Engineering
  • Translational Cancer Research

Research Interests

The Verbridge Laboratory of Integrative Tumor Ecology (LITE) is an NSF- and NIH-supported lab in the emerging field of tumor engineering. We place a particular emphasis on the development of simple engineered platforms that can provide deep insights into complex biological processes in the context of the tumor microenvironment.

We currently have major efforts in two primary areas: 1) the development of new tumor-targeted ablation modalities that target the altered physics of tumors, and 2) the development of innovative tissue-engineered models to analyze dynamic host-pathogen interactions within the context of cancer.

Education

  • Cornell University: Postdoctoral Researcher, Biomedical Engineering / Chemical and Biomolecular Engineering, 2008-2011
  • Cornell University: Ph.D., Physics, 2008 
  • Cornell University: M.S., Physics, 2007 
  • University of Rochester: B.S., Physics, 2002
  • University of Rochester: B.S., Applied Mathematics, 2002 

Awards, Honors, and Service

  • 2018: Engineering Dean's Award Faculty Fellow
  • 2017: NSF CAREER Award 
  • 2017: Joined the Scientific Reports Editorial Board 
  • 2017: Department of Biomedical Engineering and Mechanics Distinguished Leader in Research 
  • 2016: Department of Biomedical Engineering and Mechanics Leader in Research 
  • 2015: Virginia Tech Engineering Dean's Award for Outstanding New Assistant Professor 
  • 2015: Department of Biomedical Engineering and Mechanics Leader in Scholarship Award 
  • 2015: Virginia Tech Research Scholar of the Week

Recent Publications

JW Ivey, EM Wasson, N Alinezhadbalalami, A Kanitkar, W Debinski, et. al. 2019. Characterization of Ablation Thresholds for 3D-Cultured Patient-Derived Glioma Stem Cells in Response to High-Frequency Irreversible Electroporation, Research, 8081315.

MC Cox, C Deng, LB Naler, C Lu, SS Verbridge. 2019. Effects of culture condition on epigenomic profiles of brain tumor cells, ACS Biomaterials Science & Engineering 5 (3), 1544-1552.

A Umana, BE Sanders, CC Yoo, MA Casasanta, B Udayasuryan, et. al. 2019. Utilizing Whole Fusobacterium Genomes to Identify, Correct, and Characterize Potential Virulence Protein Families, Journal of bacteriology, JB. 00273-19.

EM Wasson, N Alinezhadbalalami, RM Brock, IC Allen, SS Verbridge, et. al. 2019. Understanding the role of calcium-mediated cell death in high-frequency irreversible electroporation, Bioelectrochemistry, 107369.

N Alinezhadbalalami, TA Douglas, N Balani, SS Verbridge, RV Davalos. 2019. The feasibility of using dielectrophoresis for isolation of glioblastoma subpopulations with increased stemness, Electrophoresis.

VM Ringel-Scaia, N Beitel-White, MF Lorenzo, RM Brock, KE Huie, et. al. 2019. High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity, EBioMedicine.

EL Latouche, CB Arena, JW Ivey, PA Garcia, TE Pancotto, N Pavlisko, et. al. 2018. High-frequency irreversible electroporation for intracranial meningioma: A feasibility study in a spontaneous canine tumor model, Technology in cancer research & treatment 17, 1533033818785285.

DC Aduba Jr, K Zhang, A Kanitkar, JM Sirrine, SS Verbridge, TE Long. 2018. Electrospinning of plant oil-based, non-isocyanate polyurethanes for biomedical applications, Journal of Applied Polymer Science 135 (29), 46464.

HJ Cho, SS Verbridge, RV Davalos, YW Lee. 2018. Development of an In Vitro 3D Brain Tissue Model Mimicking In Vivo-Like Pro-inflammatory and Pro-oxidative Responses, Annals of biomedical engineering 46 (6), 877-887.

I Goswami, JB Perry, ME Allen, DA Brown, MR von Spakovsky, et. al. 2018. Influence of pulsed electric fields and mitochondria-cytoskeleton interactions on cell respiration, Biophysical journal 114 (12), 2951-2964.