Scott Verbridge, Ph.D.
- Biomedical imaging
- Tissue Engineering
- Translational Cancer Research
The Verbridge Laboratory of Integrative Tumor Ecology (LITE) is an NSF- and NIH-supported lab in the emerging field of tumor engineering. We place a particular emphasis on the development of simple engineered platforms that can provide deep insights into complex biological processes in the context of the tumor microenvironment.
We currently have major efforts in two primary areas: 1) the development of new tumor-targeted ablation modalities that target the altered physics of tumors, and 2) the development of innovative tissue-engineered models to analyze dynamic host-pathogen interactions within the context of cancer.
- Cornell University: Postdoctoral Researcher, Biomedical Engineering / Chemical and Biomolecular Engineering, 2008-2011
- Cornell University: Ph.D., Physics, 2008
- Cornell University: M.S., Physics, 2007
- University of Rochester: B.S., Physics, 2002
- University of Rochester: B.S., Applied Mathematics, 2002
Awards, Honors, and Service
- 2020: Engineering Dean's Award for Research
- 2020: Liviu Librescu Award
- 2018: Engineering Dean's Award Faculty Fellow
- 2017: NSF CAREER Award
- 2017: Joined the Scientific Reports Editorial Board
- 2017: Department of Biomedical Engineering and Mechanics Distinguished Leader in Research
- 2016: Department of Biomedical Engineering and Mechanics Leader in Research
- 2015: Virginia Tech Engineering Dean's Award for Outstanding New Assistant Professor
- 2015: Department of Biomedical Engineering and Mechanics Leader in Scholarship Award
- 2015: Virginia Tech Research Scholar of the Week
Casasanta MA, Yoo CC, Udayasuryan B, Sanders BE, Umana A, Zhang Y, Peng H, Duncan AJ, Wang Y, Li L, Verbridge SS, Slade DJ, Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration, Science Signaling, 2020.
Lorenzo MF, Thomas SC, Kani Y, Hinckley J, Lee M, Adler J, Verbridge SS, Hsu F-C, Robertson JL, Davalos RV, Rossmeisl JH, Jr. Temporal Characterization of Blood–Brain Barrier Disruption with High-Frequency Electroporation. Cancers. 2019; 11(12):1850.
Alinezhadbalalami N, Douglas TA, Balani N, Verbridge SS and Davalos RV. The feasibility of using dielectrophoresis for isolation of glioblastoma subpopulations with increased stemness. Electrophoresis. 2019; 40: 2592-2600. doi:10.1002/elps.201900026
JW Ivey, EM Wasson, N Alinezhadbalalami, A Kanitkar, W Debinski, et. al. 2019. Characterization of Ablation Thresholds for 3D-Cultured Patient-Derived Glioma Stem Cells in Response to High-Frequency Irreversible Electroporation, Research, 8081315.
MC Cox, C Deng, LB Naler, C Lu, SS Verbridge. 2019. Effects of culture condition on epigenomic profiles of brain tumor cells, ACS Biomaterials Science & Engineering 5 (3), 1544-1552.
A Umana, BE Sanders, CC Yoo, MA Casasanta, B Udayasuryan, et. al. 2019. Utilizing Whole Fusobacterium Genomes to Identify, Correct, and Characterize Potential Virulence Protein Families, Journal of bacteriology, JB. 00273-19.
EM Wasson, N Alinezhadbalalami, RM Brock, IC Allen, SS Verbridge, et. al. 2019. Understanding the role of calcium-mediated cell death in high-frequency irreversible electroporation, Bioelectrochemistry, 107369.
N Alinezhadbalalami, TA Douglas, N Balani, SS Verbridge, RV Davalos. 2019. The feasibility of using dielectrophoresis for isolation of glioblastoma subpopulations with increased stemness, Electrophoresis.
VM Ringel-Scaia, N Beitel-White, MF Lorenzo, RM Brock, KE Huie, et. al. 2019. High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity, EBioMedicine.
EL Latouche, CB Arena, JW Ivey, PA Garcia, TE Pancotto, N Pavlisko, et. al. 2018. High-frequency irreversible electroporation for intracranial meningioma: A feasibility study in a spontaneous canine tumor model, Technology in cancer research & treatment 17, 1533033818785285.