Wednesday, November 28, 2018

1:30pm - 2:30pm

310 Kelly Hall – VT Campus

Dr. Brittany Taylor

Postdoctoral Research Fellow in the McKay Orthopaedic Research Laboratory

University of Pennsylvania School of Medicine 

Abstract:

Musculoskeletal injuries due to disease, traumatic injury, or repetitive activity are major problems worldwide. Tissue engineering (TE) has been heavily explored as a promising alternative strategy to overcome the many disadvantages associated with conventional repair methods. The featured studies focus on the in vitro and in vivo evaluation of two independent three-dimensional cell-free systems for enhanced (1) bone regeneration and (2) tendon repair. First, the development and characterization of a novel osteoinductive pre-vascularized scaffold composed of electrospun synthetic and collagen-based materials designed to promote early vascularization and mechanical stability for significant bone loss will be discussed. Next, the biological and mechanical implications of a biocompatible nanofibrous bilayer delivery system (BiLDS) for localized delivery of ibuprofen to mitigate inflammation in a rat rotator cuff repair model will be elucidated. This collection of work exploits the ability of these transformative technologies to provide physical and chemical cues for improved musculoskeletal tissue regeneration.

Biography:

Dr. Brittany Taylor is a versatile and self-motivated Postdoctoral Research Fellow in the McKay Orthopaedic Research Laboratory at the University of Pennsylvania School of Medicine in the Department of Orthopaedic Surgery. She is also the recipient of the prestigious Vice Provost for Research Postdoctoral Fellowship for Academic Diversity. Her current research, under the mentorship of Dr. Louis Soslowsky, is on the investigation of a drug release delivery system as a therapeutic for rotator cuff tendinopathy and the role of collagen type V on the tendon healing environment. Brittany received her B.S. in Biomedical Engineering from the University of Virginia and her Ph.D. in Biomedical Engineering from Rutgers University. She is also an alumni scholar of the esteemed Virginia Tech Post-baccalaureate Research and Education Program (VT-PREP).